Clinical Trials and Data

Our Focus

• Collaborate widely across the membership and beyond, to include affiliated partners external to the organisation, supporting approval and governance processes.

• Improve community engagement and patient access and recruitment into high quality clinical trials.

• Develop, update and strengthen our Clinical Trials and Data integration capability and capacity frameworks.

• Support and nurture clinical trial and data management sector growth, compliance, sustainability and financial return, for partners and other key stakeholders.

• Share data from our clinical trials, registries and ethics and governance processes for new knowledge and innovation to ensure better health outcomes.

• Capture technology and modern approaches to better harmonise, link, analyse and understand our data.

Projects

SPHERE has the following data driven activities currently in the pipeline:

• The Cancer Variation (CaVa) platform utilises data integration to analyse variation of cancer treatments across organisations.

• PeRson-centred Adherence Intervention Supported by Electronic medical record Data integration (PRAISED), utilises data drawn from electronic medical records in real-time to identify patients at high risk of readmission. PRAISED investigates variations in practice related to drug adherence, measuring local early readmission data to integrate administrative and clinical inputs.

• AI-ED is using artificial intelligence (AI) to promote integrated care quality for older people by reducing preventable emergency department (ED) admissions. The aim of this project is to enable older people to remain independent, functioning, and diminish disability and deterioration with the right care at the right time in the right place. It will inform early intervention approaches that empower and integrate community and primary care.

• RODE (Research and Operational Data Environment) is a distributed data platform that provides cross-jurisdictional data access. Locally built in South Eastern Sydney Local Health District (SESLHD) and eHealth NSW operated, RODE has been designed from the ground up to meet all operational, security, and governance requirements for the provision of identifiable health data for research and service management. This data platform opens up the capacity for Phase IV clinical trials and improves capacity to identify eligible clinical trial participants.

• RICH harnesses the RODE platform infrastructure to enable and monitor research collaboration activities. The technology-based RICH program will enable SPHERE members to find information on research activities and capabilities across the partnership.

For more information, contact Research Support Officer Natalie Walsh.

For more information, contact Research Support Officer Natalie Walsh.

Education and Training

SPHERE supported Education and Training resources can be searched via our Resources page.

Resource topics include:

• Good Clinical Practice (GCP)
• GCP Train the Trainer
• Introduction to HREC fundamentals
• Health Economics Workshop Sessions
• Ethics Exchange Webinar Series
• Clinical Trial Audit and Monitoring

See also external links:

Australian Clinical Trials Education Centre (A-CTEC), an Australia wide, member-based education platform, hosting a comprehensive suite of evidence- based, interactive clinical trials education opportunities suitable for a range of learning needs.

Health Translation Queensland facilitates education and training sessions to support researchers and professional staff working in the areas of research, ethics, and research integrity and governance.